当前位置:首页 > 产品展厅  > DBCO  > DBCO-PEG-FA,二苯并环辛烯-聚乙二醇-叶酸
DBCO-PEG-FA,二苯并环辛烯-聚乙二醇-叶酸
起批量(毫克 价格
>0 面议
  • 供货能力:大量
  • 最低订购量:50毫克
  • 可销售总数量:10000毫克
  • 建议零销价:45元/毫克
  • 发布日期: 2018-03-08
  • 更新日期: 2018-09-25
产品详细说明
品牌: ponsure 产地: 上海
货号: PS2-FADB 含量: 90
产品规格: 产品英文名称: DBCO-PEG-FA
CAS编号: 别名: DBCO-PEG- Folic acid
分子式:

 

二苯并环辛烯-聚乙二醇-叶酸,DBCO-PEG-FA,DBCO-PEG- Folic acid产品芃硕生物强势推出,自主研发,欢迎选购!

名称

货号

英文名、缩写

分子量

规格

DBCO-PEG-FA

PS2-FADB-5K

DBCO-PEG-FA

5000

0.1g0.5g

DBCO-PEG-FA

PS2-FADB-2K

DBCO-PEG-FA

2000

0.1g0.5g

DBCO-PEG-FA

PS2-FADB-3K

DBCO-PEG-FA

3400

0.1g0.5g

DBCO-PEG-FA

PS2-FADB-1K

DBCO-PEG-FA

1000

0.1g0.5g

DBCO-PEG-FA

PS2-FADB-10K

DBCO-PEG-FA

10000

0.1g0.5g

(备注:非常规分子量:400600。精确聚合度的小分子定制。)

 

结构式:

 

基本信息:

 

 

中文名称:二苯并环辛烯-聚乙二醇-叶酸 (DBCO-PEG-FA)

别名:DBCO-PEG-FA

英文名称:DBCO-PEG-FA,DBCO-PEG- Folic acid

CAS:-

分子量:400、600、1K、2K、3.4K、4K、5K、10K

纯度:90%以上

二苯并环辛烯-聚乙二醇-叶酸,DBCO-PEG-FA,DBCO-PEG- Folic acid产品芃硕生物强势推出,自主研发,欢迎选购!

 

应用简介:

  

DBCO PEG Folic acid, also called DBCO PEG folate, is one of Ponsure' folic acid PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG folate derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Folic acid, is also known as vitamin M, vitamin B9 or pteroyl-L-glutamic acid. Folic acid is an essential bioactive molecule for numerous biological functions. It participates in the synthesis, repairing and methylation of DNA as well as to act as a cofactor in many biological reactions. DBCO functional folic acid can be easily attached to azide functionalized molecules, particles or solid surfaces.

 

Copper-free Click Reaction Procedures:

 

Prepare the azide-containing sample in reaction buffer. Add DBCO conjugate to azide containing sample. Recommendation: Add 1 mole equivalent of limiting reagent to 1.5-3.0 mole equivalents of highest abundance reagent. Incubate the reaction at room temperature for 2-4 hours or 2-12 hours at 4 degree celcius. The reaction is now ready for purification.

 

物理性质:

 

状态:淡黄色到黄色固体,或者半固体,取决于分子量。

溶解性:溶于DMSO。

保持条件:-20℃长期保存,避光,干燥。

注意事项:取用一定要干燥,避免频繁的溶解和冻干。

反应性:DBCO于含有N3基团的反应。

二苯并环辛烯-聚乙二醇-叶酸,DBCO-PEG-FA,DBCO-PEG- Folic acid产品芃硕生物强势推出,自主研发,欢迎选购!

 

技术指标:

 

纯度(PEG):90%以上

取代率(DBCO):90%以上

取代率(FA):90%以上

分散系数(PDI):小于等于1.05

分析:COA、GPC、NMR、MALDI-TOF

 

相关产品推荐:

MPEG-DBCO

DBCO-PEG-NH2

DBCO-PEG-COOH

DBCO-PEG-NHS

DBCO-PEG-SH

DBCO-PEG-ACRL

DBCO-PEG-ACA

DBCO-PEG-DSPE

DBCO-PEG-FITC

DBCO-PEG-RB

DBCO-PEG-MAL

DBCO-PEG-FA

DBCO-PEG-BIOTIN

DBCO-PEG-OH

DBCO-PEG-OPSS

LA-PEG-DBCO

4ARM-PEG-DBCO

 

二苯并环辛烯-聚乙二醇-叶酸,DBCO-PEG-FA,DBCO-PEG- Folic acid产品芃硕生物强势推出,自主研发,欢迎选购!